| Electroplankton: Luminarrow | DS | E | | Nov 23, 2009 | Nintendo |
| Electroplankton: Marine-Crystals | DS | E | | Nov 23, 2009 | Nintendo |
| Electroplankton: Nanocarp | DS | E | | Nov 9, 2009 | Nintendo |
| Electroplankton: Rec-Rec | DS | E | | Nov 9, 2009 | Nintendo |
| Electroplankton: Sun-Animalcule | DS | E | | Nov 23, 2009 | Nintendo |
| Electroplankton: Trapy | DS | E | | Nov 9, 2009 | Nintendo |
| Electroplankton: Varvoice | DS | E | | Nov 23, 2009 | Nintendo |
| Elite Beat Agents | DS | E10+ | 87 | Nov 6, 2006 | iNiS |
| Endless Ocean | WII | E | 72 | Jan 21, 2008 | Arika |
| Endless Ocean: Blue World | WII | E10+ | 76 | Feb 22, 2010 | Arika |
| Eternal Darkness: Sanity's Requiem | GC | M | 92 | Jun 23, 2002 | Silicon Knights |
| Ever Oasis | 3DS | E10+ | 76 | Jun 23, 2017 | GREZZO |
| Everybody 1-2-Switch! | Switch | E | 56 | Jun 30, 2023 | Nintendo |
| Everybody Votes | WII | | | Feb 14, 2007 | Nintendo |
| Excite Truck | WII | E | 72 | Nov 19, 2006 | Monster Games Inc. |
| Excitebike | WII | E | | Mar 19, 2007 | Nintendo |
| Excitebike 64 | N64 | E | 88 | Apr 30, 2000 | Left Field Productions |
| Excitebike: World Rally | WII | E | 70 | Nov 9, 2009 | Monster Games Inc. |
| Excitebots: Trick Racing | WII | E | 77 | Apr 20, 2009 | Monster Games Inc. |
| Excitebots: Trick Racing | WIIU | | | Dec 15, 2016 | Nintendo |